A Traditional Medicine-Based Combination of Bamboo Salt and Egg White-Chalcanthite Ameliorates Atopic Dermatitis

Bamboo salt and egg white-chalcanthite mixture has been prescribed for relieving the inflammation of atopic dermatitis in Hamyang, Gyeongsangnam-do, Korea. This study was conducted to demonstrate effect on cell animal models using a combination bamboo with white-chalcanthite, which have used as folk remedies inflammatory conditions. Based vitro experiment, 1:20 shown inhibit release beta-hexosaminidase histamine rat basophilic leukemia line RBL-2H3 by sensitizing immunoglobulin E inducing allergic responses dinitrophenyl well expression cytokines mediators dose-dependent manner lipopolysaccharide-treated mouse macrophage RAW 264.7 cells. Furthermore, its at different mixing ratios showed decrease mediators. Dinitrochlorbenzene applied NC/Nga mice 6 w induce vivo model. After 4 administration test substance, decreased visually dermal hyperplasia/inflammation, mast cell/eosinophils counts degree nerve fiber infiltration were according histopathological examination. In addition, secretion rate interferon gamma high-dose treated group lower than that control group. These results show effectively relieves skin it might be promising mineral agent symptoms dermatitis.